Silver Spring, MD – October 8, 2025, 3 PM EDT —
eCSEPTIONOL LLC proudly announces the launch of Quelle365™, a revolutionary Wellness Supplement and Dog Food Topper designed to address canine discomfort across all life stages. This vitality topper introduces a new standard in joint relief and mitochondrial health for dogs, offering effective daily relief from inflammation, arthritis, and discomfort when sprinkled on any dog food.
Quelle365™ provides advanced mitochondrial inflammation management, delivering increased mobility, reduced pain, and improved vitality across all breeds and ages.
ONE POWERFUL FORMULA. FIVE PROVEN INGREDIENTS. TOTAL WELLNESS.
Quelle365™ combines five GRAS-qualified natural ingredients into one daily supplement powder:
- Palmitoylethanolamide (PEA)
- Beta-Caryophyllene (BCP)
- Docosahexaenoic Acid (DHA)
- Astaxanthin (ASX)
- Quercetin (QUE)
Each is backed by scientific research for inflammation, antioxidant, and mitochondrial support.
Why Quelle365™?
Multi-Modal Anti-Inflammatory Action
- Palmitoylethanolamide (PEA): Regulates immune signaling and pain via the endocannabinoid system. Reduces itch, pain, and allergic responses at their root cause.
- Beta-Caryophyllene (BCP): Selective CB2 receptor agonist offering potent anti-inflammatory effects without psychoactivity. Helps reduce rashes, pain, and allergic reactions.
- Docosahexaenoic Acid (DHA): Essential omega-3 fatty acid that reduces inflammation, supports joint health, and preserves cognitive function.
- Astaxanthin (ASX): A super-antioxidant 6,000× stronger than Vitamin C that protects organs and maintains mobility and coat quality.
- Quercetin (QUE): Natural flavonoid with antihistamine and anti-inflammatory properties that help prevent cognitive decline and systemic inflammation.
All ingredients are pharmaceutically formulated for maximum bioavailability.
Mitochondrial Wellness: Why It Matters
Mitochondrial dysfunction drives chronic inflammation, joint pain, cognitive decline, and poor recovery from illness. Quelle365™ supports cellular energy and mitochondrial repair, addressing the root of canine chronic conditions like arthritis and immune weakness.
Who Benefits
- Senior Dogs: Relief from arthritis, cognitive decline, and joint pain.
- Active Dogs: Faster recovery and enhanced flexibility.
- Allergy-Prone Dogs: Natural itch and rash reduction.
- All Breeds & Ages: Preventive wellness and immune support.
- Post-Surgery / Chronic Conditions: Improved healing and comfort.
Key Results
- Reduced systemic inflammation and organ dysfunction.
- Enhanced joint comfort, mobility, and skin health.
- Healthier coat and improved cognition.
- Stronger immune response and vitality.
Setting a New Standard in Dog Wellness
Backed by Science
- All ingredients GRAS-qualified for safety and efficacy.
- Supported by peer-reviewed veterinary studies.
- Patented multi-pathway formulation ensures synergy and performance.
- Active compounds cross the blood-brain barrier for neurological protection.
Market Opportunity
- Joint supplement for dogs projected to exceed $2.1 B by 2032 (6.5% CAGR).
- Over 50% of dogs experience joint discomfort linked to inflammation.
- Functional, health-focused dog treats are leading industry growth.
Competitive Advantages
- First supplement combining all five powerhouse ingredients in one.
- Reduces cost and complexity for pet owners.
- Veterinary-grade efficacy at consumer prices.
- Multi-modal inflammation management and unique mitochondrial focus.
Table: Quelle365™ Ingredients — Mechanistic Properties & Literature
| Ingredient | Anti-Inflammatory Property | Antioxidant Property | Mitochondrial Repair Property | Key Citations |
|---|---|---|---|---|
| Palmitoylethanolamide (PEA) | Inhibits NF-κB signaling; reduces cytokines and chronic pain (Zhao 2025) | Reduces oxidative stress; protects neuronal cells (Cristiano 2018) | Restores mitochondrial respiration and ATP levels (Scuderi 2022) | Zhao 2025 Cristiano 2018 Scuderi 2022 |
| Beta-Caryophyllene (BCP) | Selective CB2 agonist; suppresses inflammatory mediators (Horváth 2024, Lou 2021) | Scavenges free radicals; boosts antioxidant defenses (Ames-Sibin 2018) | Restores enzyme activity in diabetes and ischemia models (Horváth 2024) | Horváth 2024 Lou 2021 Ames-Sibin 2018 |
| Docosahexaenoic Acid (DHA) | Reduces pro-inflammatory cytokines; generates resolvins and protectins (Tan 2025) | Promotes antioxidant enzyme activity; reduces mitochondrial ROS (Zhao 2021) | Enhances mitochondrial biogenesis and energy resilience (Zhao 2021) | Tan 2025 Zhao 2021 |
| Astaxanthin (ASX) | Suppresses inflammatory mediators; protects tissue (Battaglia 2024) | Potent ROS scavenger; supports membrane stability (Battaglia 2024) | Prevents ATP loss and oxidative stress (Battaglia 2024) | Battaglia 2024 |
| Quercetin (QUE) | Inhibits histamine release; reduces allergic and systemic inflammation (Wang 2023) | Neutralizes ROS; protects neurons and organs (Wang 2023) | Prevents mitochondrial dysfunction and stabilizes bioenergetics (Wang 2023) | Wang 2023 |
Commitment to Safety & Compliance
Quelle365™ contains only Generally Recognized as Safe (GRAS) ingredients and complies with FDA canine supplement regulations.
This product is not intended to diagnose, treat, cure, or prevent any disease.
About eCSEPTIONOL LLC
Founded in 2024, eCSEPTIONOL LLC pioneers mitochondrial-targeted wellness solutions for pets and people. The company develops evidence-based supplements to combat chronic disease and extend healthy lifespan using safe, natural ingredients.
Quelle365™ — Where Science Meets Wellness for Every Dog, Every Day.
Bob Rager
✉️ bobrager@mac.com
Wellness supplement, Dog food topper, Joint supplement for dogs, Mobility, Arthritis relief, Multi-modal inflammation management, Advanced canine health, Dog vitality product, Pet wellness, Mitochondrial support.
